Koichi Noguchi Selected Research

tPA stop

4/2007

Tissue type plasminogen activator induced in rat dorsal horn astrocytes contributes to mechanical hypersensitivity following dorsal root injury.

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Koichi Noguchi Research Topics

Disease

43	Neuralgia (Stump Neuralgia) 10/2021 - 09/2002
42	Pain (Aches) 04/2022 - 09/2002
37	Hyperalgesia 01/2021 - 02/2001
25	Hypersensitivity (Allergy) 04/2022 - 05/2003
22	Inflammation (Inflammations) 01/2022 - 05/2003
19	Peripheral Nerve Injuries 01/2021 - 02/2001
5	Spinal Cord Injuries (Spinal Cord Injury) 01/2021 - 04/2002
3	Colitis 12/2020 - 01/2014
3	Chronic Pain 10/2016 - 05/2006
3	Taste Disorders (Taste Disorder) 09/2015 - 03/2002
3	Neurogenic Inflammation 11/2013 - 07/2007
3	Visceral Pain 01/2013 - 04/2008
2	Dyspepsia (Indigestion) 04/2022 - 01/2022
2	Cold Hypersensitivity 10/2021 - 08/2006
2	Ganglion Cysts (Ganglion) 09/2015 - 03/2002
2	Radiculopathy (Radiculopathy, Cervical) 04/2007 - 09/2002
2	Mononeuropathies (Mononeuritis Multiplex) 05/2005 - 01/2002
2	Neuritis (Polyneuritis) 03/2003 - 09/2002
1	Reperfusion Injury 03/2022
1	Somatoform Disorders (Somatoform Disorder) 10/2021
1	Abdominal Pain (Pain, Abdominal) 12/2020
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2019
1	Paralysis (Palsy) 01/2018
1	Cognitive Dysfunction 10/2016

Drug/Important Bio-Agent (IBA)

15	Protein Kinases (Protein Kinase)IBA 01/2021 - 05/2003
14	p38 Mitogen-Activated Protein KinasesIBA 01/2021 - 04/2004
11	Mitogen-Activated Protein KinasesIBA 01/2013 - 05/2003
8	Messenger RNA (mRNA)IBA 01/2018 - 04/2001
8	Adenosine Triphosphate (ATP)IBA 01/2013 - 09/2002
7	Nerve Growth Factor (NGF)IBA 03/2015 - 09/2002
6	AnkyrinsIBA 01/2021 - 10/2012
6	Brain-Derived Neurotrophic Factor (BDNF)IBA 09/2011 - 09/2002
6	OligodeoxyribonucleotidesIBA 06/2008 - 09/2005
5	Ion Channels (Ion Channel)IBA 01/2021 - 07/2003
5	Capsaicin (Zostrix)FDA Link 01/2016 - 09/2002
4	Freund's AdjuvantIBA 01/2022 - 05/2003
4	Analgesics (Analgesic Drugs)IBA 01/2022 - 05/2006
4	Proteins (Proteins, Gene)FDA Link 01/2021 - 02/2001
4	LeukotrienesIBA 09/2015 - 04/2010
4	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 08/2012 - 03/2003
4	U 0126 (UO 126)IBA 04/2008 - 09/2002
4	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 09/2007 - 05/2003
3	Dinoprostone (PGE2)FDA Link 01/2022 - 01/2019
3	TRPA1 Cation ChannelIBA 01/2021 - 05/2011
3	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 01/2019 - 06/2013
3	CytokinesIBA 01/2018 - 03/2008
3	Interleukin-18 (Interleukin 18)IBA 01/2017 - 11/2008
3	2,3,4-tri-O-acetylarabinopyranosyl isothiocyanate (AITC)IBA 01/2017 - 05/2008
3	Transient Receptor Potential ChannelsIBA 11/2013 - 11/2006
3	Tryptases (Tryptase)IBA 08/2012 - 05/2004
3	TrypsinIBA 08/2012 - 05/2004
3	salicylhydroxamic acid (SHAM)IBA 01/2012 - 09/2002
3	Nerve Growth Factors (Neurotrophins)IBA 05/2006 - 09/2002
2	Formaldehyde (Formol)FDA Link 01/2022 - 05/2011
2	Calcium Channels (Calcium Channel)IBA 03/2021 - 01/2018
2	LipidsIBA 01/2021 - 09/2010
2	ProstaglandinsIBA 01/2021 - 06/2013
2	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 03/2017 - 06/2013
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 09/2015 - 01/2002
2	Purinergic P2 Receptors (ADP Receptor)IBA 02/2015 - 08/2012
2	Small Interfering RNA (siRNA)IBA 06/2014 - 09/2011
2	Serotonin (5 Hydroxytryptamine)IBA 06/2014 - 09/2011
2	BradykininIBA 06/2013 - 05/2008
2	Purinergic Receptors (Receptors, Purine)IBA 01/2013 - 10/2012
2	Peptide Hydrolases (Proteases)FDA Link 08/2012 - 05/2004
2	Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule)IBA 06/2011 - 02/2007
2	Mitogen-Activated Protein Kinase 3IBA 01/2010 - 04/2008
2	SB 203580IBA 04/2008 - 12/2004
2	Adenosine (Adenocard)FDA LinkGeneric 03/2008 - 04/2004
2	Tissue Plasminogen Activator (Alteplase)FDA Link 04/2007 - 01/2004
2	KN 93IBA 05/2005 - 04/2005
2	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 05/2005 - 04/2005
2	Peptides (Polypeptides)IBA 04/2005 - 04/2005
2	MAP Kinase Kinase 1IBA 12/2004 - 05/2003
1	Yi-Gan SanIBA 04/2022
1	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2022
1	Gastrin-Releasing PeptideIBA 01/2022
1	phrixotoxin-2IBA 10/2021
1	Voltage-Gated Potassium Channels (Voltage-Gated Potassium Channel)IBA 10/2021
1	Opiate AlkaloidsIBA 10/2021
1	UbiquitinIBA 01/2021
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2021
1	Prostaglandins EIBA 01/2021
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2021
1	Plant ExtractsIBA 12/2020
1	Mesalamine (Mesalazine)FDA LinkGeneric 12/2020
1	PotassiumIBA 01/2019
1	Therapeutic UsesIBA 01/2018
1	Interleukin-4 Receptors (Interleukin 4 Receptor)IBA 01/2018
1	Interleukin-4 (Interleukin 4)IBA 01/2018
1	Pregabalin (Lyrica)FDA Link 01/2018
1	prostacyclin synthetase (prostacyclin synthase)IBA 03/2017
1	2- (1,3- dimethyl- 2,6- dioxo- 1,2,3,6- tetrahydro- 7H- purin- 7- yl)- N- (4- isopropylphenyl)acetamideIBA 06/2016
1	Sulfates (Sulfates, Inorganic)IBA 06/2016

Therapy/Procedure

9	Therapeutics 04/2022 - 05/2005
8	Spinal Injections 01/2016 - 05/2003
6	Ligation 01/2012 - 09/2002
4	Axotomy 04/2004 - 05/2003
2	Rhizotomy 11/2004 - 07/2004
1	Activities of Daily Living (ADL) 10/2016